Cycas revoluta (sago palm) poisoning in the dog
5-month-old French Bulldog that chewed several seeds of a garden Cycas revoluta. A few hours later it is vomiting and lethargic.
Which statement is correct?
chevron_right Show answer and explanation
A. Only the leaves are toxic; the seeds are not
All parts of the plant are toxic, and the seeds contain the most toxin.
B. Gastrointestinal signs are mild and self-limiting; no follow-up is needed
The initial vomiting may be followed by acute liver failure over the next days. Without laboratory monitoring it goes unnoticed until it is too late.
C. N-acetylcysteine is a specific antidote that reverses the toxicity
There is no antidote. N-acetylcysteine and other antioxidants are used as support, without evidence that they reverse the injury.
D. All parts are toxic, especially the seeds: acute liver failure may follow the gastroenteritis, so decontaminate, hospitalise and monitor enzymes, blood glucose and coagulation
Correct. Cycasin causes gastroenteritis within hours and hepatic necrosis within 1–3 days; it can also cause neurological signs. Treatment is supportive and mortality is considerable.
lightbulb Key takeaway
Cycas revoluta is a very common ornamental plant in gardens and terraces in Spain. Warn puppy owners. Monitor ALT, bilirubin, blood glucose and coagulation for at least 72 hours even if the dog improves.
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Updated: October 31, 2026 · Educational content for veterinary professionals. It does not replace current clinical guidelines or the judgement of the attending veterinarian.