C6-T2 lesion in the dog: the 'two-engine' gait
8-year-old large-breed crossbred dog with progressive difficulty walking over 2 months. Mental status and cranial nerves are normal; mild pain on neck extension.
| Parameter | Result | Reference |
|---|---|---|
| Thoracic limbs | Short stride; reduced withdrawal; reduced tone | Normal |
| Pelvic limbs | Long, ataxic stride; normal to increased reflexes; increased tone | Normal |
| Postural reactions | Delayed in all four limbs | Normal |
Where is the lesion located?
chevron_right Show answer and explanation
A. C1-C5 spinal cord
With a C1-C5 lesion the thoracic limbs would show upper motor neuron signs (normal or increased reflexes and tone), not a reduced withdrawal reflex with hypotonia.
B. C6-T2 spinal cord
Correct. Lower motor neuron signs in the thoracic limbs (the lesion involves the cell bodies or roots of the cervical intumescence) and upper motor neuron signs in the pelvic limbs: short strides in front and long, ataxic strides behind, the 'two-engine' gait.
C. T3-L3 spinal cord
With a T3-L3 lesion the thoracic limbs are normal. Here they are clearly affected.
D. Polyradiculoneuritis (generalised neuromuscular disease)
It would cause lower motor neuron signs in all four limbs. Pelvic limbs with normal or increased reflexes and increased tone do not fit.
lightbulb Key takeaway
In C6-T2 lesions check the panniculus reflex and look for Horner syndrome. Common causes in this region: C6-C7 disc disease, cervical spondylomyelopathy (wobbler syndrome) in large breeds, fibrocartilaginous embolism and nerve sheath tumours, which often begin with thoracic limb lameness.
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Updated: October 31, 2026 · Educational content for veterinary professionals. It does not replace current clinical guidelines or the judgement of the attending veterinarian.