Acute polyradiculoneuritis in dogs: management and prognosis
6-year-old crossbreed fed raw chicken, which started with pelvic limb weakness 3 days ago and today cannot stand. Flaccid tetraparesis, markedly reduced spinal reflexes in all four limbs, hoarse bark, preserved sensation with mild hyperaesthesia. Voluntary urination and normal swallowing.
Which statement about management and prognosis is correct?
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A. Immunosuppressive prednisolone speeds recovery and is the treatment of choice
Although it is an immune-mediated disease, there is no evidence that corticosteroids shorten recovery, and they increase the risk of infection and muscle wasting.
B. Intensive supportive care and monitoring of respiratory function; most dogs recover within weeks to months
Correct. Padded bedding, regular turning, physiotherapy, bladder care and nutrition. Monitor ventilation: if respiratory muscles are affected, mechanical ventilation may be needed. Mild cases recover within a few weeks, while severe ones may take months.
C. The prognosis is poor and euthanasia is advised if the dog is not walking within 7 days
Recovery is slow but the prognosis is usually good with proper nursing. One week without improvement does not indicate a poor prognosis.
D. Give antitoxin, because the condition is caused by a neurotoxin
Antitoxin is for botulism. Polyradiculoneuritis is an immune-mediated neuropathy of the ventral roots, not an intoxication.
lightbulb Key takeaway
In Europe it has been associated with raw chicken consumption and Campylobacter infection; in America, with raccoon saliva (Coonhound paralysis). Cranial nerves are usually spared apart from dysphonia and facial weakness. Intravenous human immunoglobulin has been used, but evidence is limited. It may recur with new exposures.
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Updated: October 31, 2026 · Educational content for veterinary professionals. It does not replace current clinical guidelines or the judgement of the attending veterinarian.