Laryngeal paralysis in the geriatric Labrador: GOLPP
12-year-old Labrador Retriever with inspiratory stridor that worsens in hot weather, a hoarse bark for months and scuffing of the hind nails. The owners say it sometimes coughs when drinking.
Which statement about its disease is correct?
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A. It is an isolated idiopathic laryngeal paralysis; the hind-limb weakness is due to osteoarthritis
Most 'idiopathic' laryngeal paralyses in older dogs are the first manifestation of a generalised polyneuropathy; attributing the weakness to osteoarthritis overlooks its progression.
B. It is usually due to hypothyroidism, and levothyroxine supplementation resolves the paralysis
Hypothyroidism should be ruled out, but a causal link has not been shown and supplementation rarely reverses laryngeal paralysis.
C. It is acquired myasthenia gravis and should be treated with pyridostigmine
Myasthenia can cause laryngeal dysfunction and megaoesophagus, but presents with exercise-induced weakness and is confirmed by acetylcholine receptor antibodies. Here the slow, progressive picture suggests polyneuropathy.
D. It is part of a progressive geriatric polyneuropathy (GOLPP) that also affects the oesophagus and limbs, increasing the risk of aspiration
Correct. In GOLPP (geriatric onset laryngeal paralysis polyneuropathy) laryngeal paralysis is the first sign, followed by hind-limb weakness and oesophageal dysmotility. Dysphagia and coughing when drinking warn of a higher risk of aspiration pneumonia after lateralisation.
lightbulb Key takeaway
Before operating on laryngeal paralysis, look for signs of polyneuropathy and oesophageal dysfunction (neurological exam, history of regurgitation, thoracic radiographs). They do not contraindicate surgery, but they worsen the long-term prognosis and must be explained to owners.
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Updated: October 31, 2026 · Educational content for veterinary professionals. It does not replace current clinical guidelines or the judgement of the attending veterinarian.