Inducing emesis in cats: which drug to use
2-year-old domestic shorthair that bit into and swallowed several of its owner's venlafaxine capsules 30 minutes ago. It is alert and has no clinical signs.
What is the most appropriate way to induce emesis?
chevron_right Show answer and explanation
A. Intramuscular dexmedetomidine and, after vomiting, reversal with atipamezole
Correct. In cats, alpha-2 agonists (dexmedetomidine or xylazine) are the most effective emetics. Sedation and bradycardia are reversed with atipamezole once the cat has vomited.
B. Intravenous apomorphine, as in dogs
In cats apomorphine is unreliable because their chemoreceptor trigger zone responds mainly to alpha-2 rather than dopaminergic stimulation; it can also cause excitement.
C. Oral 3% hydrogen peroxide
In cats hydrogen peroxide is unreliable and can cause severe haemorrhagic gastritis and oesophagitis. It is not recommended.
D. A teaspoon of salt on the back of the tongue
Salt is an unreliable emetic and can cause severe hypernatraemia with neurological signs. It is not recommended in any species.
lightbulb Key takeaway
In cats, use an alpha-2 agonist to induce emesis and have atipamezole ready. It is less effective than apomorphine in dogs, so do not delay activated charcoal or other measures if the cat does not vomit. Venlafaxine is attractive to cats and causes serotonin syndrome (agitation, mydriasis, tachycardia, hyperthermia).
Test yourself with 10 random questions
Emergency and critical care · 100 questions, a different test every time
Related questions
Updated: October 31, 2026 · Educational content for veterinary professionals. It does not replace current clinical guidelines or the judgement of the attending veterinarian.